Glaser, N., Barnett, P., McCaslin, I., Nelson, D., Trainor, J., Louie, J., … & Kuppermann, N. (2001). New England Journal of Medicine.

Abstract Conclusions:

Children with diabetic ketoacidosis who have low partial pressures of arterial carbon dioxide and high serum urea nitrogen concentrations at presentation and who are treated with bicarbonate are at increased risk for cerebral edema.